Daily low-dose aspirin and healthy life span

Daily low-dose aspirin found to have no effect on healthy life span in older people

I remember this being a typical Dr. Oz recommendation years ago, he was always talking about the need to take aspirin for life extension. Seems 60 million americans take aspirin every day, and only quite recently even Dr. Oz walked backed on this now…

Despite the lack of positive effects on the healthspan among the elderlyes (70+ y.o.), baby aspirin remains important for prevention CVD yet required harms/benefits analysis:

"These new findings provide an impetus to review aspirin use for primary prevention in the context of foundational population health principles:

  • Select treatments for which potential benefits outweigh harms.
  • Understand the magnitude of benefits and harms from the patient’s perspective.
  • Prefer treatment options with smaller numbers needed to treat (NNTs) (eg, statins vs aspirin).
  • Favor initiation of any given treatment in patient subpopulations with smaller NNTs.
  • Use patient shared decision-making (SDM), particularly when ambiguity about the balance of potential harms and benefits is present.
  • Pursue a comprehensive prevention approach that includes drug and nondrug strategies."

https://jamanetwork.com/journals/jama/fullarticle/2737592

Chiang KF, Shah SJ, Stafford RS. A Practical Approach to Low-Dose Aspirin for Primary Prevention. JAMA. Published online June 28, 2019. DOI:10.1001/jama.2019.8388

1 Like

https://esc365.escardio.org/Congress/ESC-CONGRESS-2019/Late-Breaking-Science-in-Cardiovascular-Pharmacology/202022-a-risk-based-approach-to-the-role-of-aspirin-on-cardiovascular-risk-reduction-in-a-healthy-older-cohort